 Description for Sphingomyelin |
| Lipid |
Sphingomyelin |
| Species |
Homo sapiens |
| Sphingomyelin identified in exosomes derived from the following tissue/cell type |
|
Astrocytes
|
25498500
|
|
Glioblastoma cells
|
25498500
|
|
Mesenchymal stem cells
|
25669974
|
|
Prostate cancer cells
|
25519911
|
|
Prostate cancer cells
|
25519911
|
|
Prostate cancer cells
|
25519911
|
| Experiment description of studies that identified Sphingomyelin in exosomes |
| 1 |
| Experiment ID |
273 |
| Identified molecule |
Lipid 
|
| Identification method |
Thin-layer chromatography
|
| PubMed ID |
25498500
|
| Organism |
Homo sapiens |
| Experiment description |
Effective internalization of U251-MG-secreted exosomes into cancer cells and characterization of their lipid components. |
| Authors |
Toda Y, Takata K, Nakagawa Y, Kawakami H, Fujioka S, Kobayashi K, Hattori Y, Kitamura Y, Akaji K, Ashihara E. |
| Journal name |
Biochem Biophys Res Commun
|
| Publication year |
2015 |
| Sample |
Astrocytes |
| Sample name |
Astrocytes |
| Molecules identified in the study |
Lipids |
| Methods used in the study |
Thin layer chromatography |
|
|
| 2 |
| Experiment ID |
272 |
| Identified molecule |
Lipid
|
| Identification method |
Thin-layer chromatography
|
| PubMed ID |
25498500
|
| Organism |
Homo sapiens |
| Experiment description |
Effective internalization of U251-MG-secreted exosomes into cancer cells and characterization of their lipid components. |
| Authors |
Toda Y, Takata K, Nakagawa Y, Kawakami H, Fujioka S, Kobayashi K, Hattori Y, Kitamura Y, Akaji K, Ashihara E. |
| Journal name |
Biochem Biophys Res Commun
|
| Publication year |
2015 |
| Sample |
Glioblastoma cells |
| Sample name |
U251 |
| Molecules identified in the study |
Lipids
Protein |
| Methods used in the study |
Thin layer chromatography
Western blotting |
|
|
| 3 |
| Experiment ID |
261 |
| Identified molecule |
Lipid
|
| Identification method |
LC-ESI-MS
|
| PubMed ID |
25669974
|
| Organism |
Homo sapiens |
| Experiment description |
Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins,and metabolites |
| Authors |
Krishna C. Vallabhaneni1, Patrice Penfornis, Santosh Dhule, Francois Guillonneau, Kristen V. Adams, Yin Yuan Mo, Rui Xu, Yiming Liu, Kounosuke Watabe, Mohan C. Vemuri and Radhika Pochampally |
| Journal name |
Oncotarget
|
| Publication year |
2014 |
| Sample |
Mesenchymal stem cells |
| Sample name |
hMSCs |
| Molecules identified in the study |
Protein
miRNA
Lipids
Metabolites |
| Methods used in the study |
Western blotting
Mass spectrometry
RT-PCR
Sequencing |
|
|
| 4 |
| Experiment ID |
245 |
| Identified molecule |
Lipid
|
| Identification method |
LC-MS
|
| PubMed ID |
25519911
|
| Organism |
Homo sapiens |
| Experiment description |
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells |
| Authors |
Phuyal S, Skotland T, Hessvik NP, Simolin H, Overbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A. |
| Journal name |
J Biol Chem
|
| Publication year |
2015 |
| Sample |
Prostate cancer cells |
| Sample name |
PC-3 - Ethanol treated (control) |
| Molecules identified in the study |
Lipids
Protein |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|
| 5 |
| Experiment ID |
246 |
| Identified molecule |
Lipid
|
| Identification method |
LC-MS
|
| PubMed ID |
25519911
|
| Organism |
Homo sapiens |
| Experiment description |
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells |
| Authors |
Phuyal S, Skotland T, Hessvik NP, Simolin H, Overbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A. |
| Journal name |
J Biol Chem
|
| Publication year |
2015 |
| Sample |
Prostate cancer cells |
| Sample name |
PC-3 - sn-1-O-hexadecylglycerol treated |
| Molecules identified in the study |
Lipids |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|
| 6 |
| Experiment ID |
247 |
| Identified molecule |
Lipid
|
| Identification method |
LC-MS
|
| PubMed ID |
25519911
|
| Organism |
Homo sapiens |
| Experiment description |
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells |
| Authors |
Phuyal S, Skotland T, Hessvik NP, Simolin H, Overbye A, Brech A, Parton RG, Ekroos K, Sandvig K, Llorente A. |
| Journal name |
J Biol Chem
|
| Publication year |
2015 |
| Sample |
Prostate cancer cells |
| Sample name |
PC-3 - DL- palmitin treated |
| Molecules identified in the study |
Lipids |
| Methods used in the study |
Western blotting
Mass spectrometry |
|
|